3 Takeaways™

Mark Cuban told people that television would eventually be delivered over the internet.  Everybody thought he was an idiot. Now, Cuban is making another prediction that runs counter to what we all believe, but this time it's about A.I. Few people have made as many big bets across as many industries as Mark Cuban. The billionaire entrepreneur and investor has built businesses in technology and media, transformed the NBA's Dallas Mavericks, and is now taking on prescription drug companies with Cost Plus Drugs. He discusses: ● What everyone may be getting wrong about AI ● What he sees happening t

What if the president can act before Congress has time to stop him? As former U.S. Secretary of Homeland Security, former General Counsel of the Department of Defense, and a member of the National Security Council, Jeh Johnson has advised presidents on war, terrorism, cyber threats, and some of the country’s most consequential national security decisions. He has seen what happens when the pressure to “do something” collides with incomplete intelligence, rapidly changing facts, political pressure, and enormous presidential power. He discusses: ● Why “Mr. President, do something” can be dangerou

What if trying harder is sometimes exactly the wrong thing to do? Angela Duckworth, University of Pennsylvania psychologist, MacArthur Fellow, and author of the #1 New York Times bestseller Grit, has spent years studying achievement. In her new book, Situated, she explores why perseverance alone isn't enough. She discusses: How Angela and her husband nearly “gritted” their way out of their marriage How much your environment shapes who you become The small change that can make good habits easier Why parents may be asking the wrong question about their children How peer pressure can become a fo

What can we do when doing the morally “right” thing produces worse outcomes? And what if some of society’s strongest moral instincts are preventing us from solving problems we all agree are terrible? Alvin Roth is a Stanford professor and Nobel Prize-winning economist whose work has helped redesign real-world systems, including kidney exchanges and the way doctors are matched with hospitals. His new book, Moral Economics, tackles a harder category of problems: markets and behaviors we find morally objectionable, even when banning them may create consequences we don’t want. He discusses: Why n

Could America build the world’s best AI and still lose the AI race? What if the biggest threat to America’s lead isn’t China’s technology, but our own fear of using it? Katrina Mulligan is Head of National Security Partnerships at OpenAI and previously served in senior roles at the Department of Defense, National Security Council, and Department of Justice. Few people have seen both Washington and frontier AI development from the inside. She argues that AI is no longer a technology question for the future. It is becoming core infrastructure for economic strength, national security, and the way

What if your brain isn’t showing you the world as it truly is? Journalist, professor, and author of "A World Appears: A Journey into Consciousness" Michael Pollan explores one of the deepest questions of all: why do we experience anything in the first place?  He discusses: What consciousness actually is Why the brain predicts reality instead of simply taking it in How perception may be a kind of “controlled hallucination” Why we may see the world in the most useful way, not the most accurate way What animals, plants, and AI reveal about consciousness Why feelings may be central to being consc

Why would the world’s largest country risk everything to destroy a smaller neighbor? What is it about Ukraine that poses a greater threat to Vladimir Putin than any army? Pulitzer Prize-winning historian and The Atlantic writer Anne Applebaum has spent decades studying Russia, Ukraine, and authoritarian regimes. She argues that the war is being fought over far more than territory and that the outcome will reshape democracy, military power, and global politics. She discusses: ● What Putin was really trying to prevent when he invaded Ukraine ● Why nearly everyone underestimated the Ukrainian peo

How does someone steal the Mona Lisa from the Louvre and simply walk away?  And how did an even more brazen crew rob the same museum in broad daylight last year with just a cherry picker and some power tools? The real stories are stranger than Hollywood and best-selling author Noah Charney knows them all. One of the world’s leading experts on art crime, he has advised museums, governments, and law enforcement agencies around the world.   It turns out that stealing priceless art is often surprisingly easy. It’s turning the art into money that’s nearly impossible. He explains: ◼ How a thief had

Artificial intelligence could change almost everything. John Hennessy thinks we're still asking the wrong questions. As Chairman of Alphabet and one of the pioneers of modern computing, Hennessy has helped shape some of the biggest technology revolutions of the past half century.  He explains what today's AI can - and can’t - actually do, what would qualify as artificial general intelligence, and why the greatest impact of AI may come from amplifying human capability rather than replacing it. He discusses: The one capability that still separates humans from machines. What would have to happen

Why do some people instantly draw us in? Olivia Fox Cabane reveals that charisma is not a gift. It is a skill - and most of us misunderstand what creates it. In this episode, you’ll learn: The three qualities that make someone charismatic Why introverts can be highly magnetic How people judge you before you speak Why presence matters more than performance The surprising link between confidence and self-compassion Simple ways to become more charismatic immediately Charisma is not just how people feel about you. It is how you make them feel about themselves. Olivia Fox Cabane is the author of

Everyone knows where the last generation of great technology companies came from. The more interesting question is where the next generation will. Mehran Gul spent years studying the world's most successful innovation hubs to understand why some places repeatedly create breakthrough companies while others never quite do. He shares surprising insights about China's rise, Silicon Valley's future, and why artificial intelligence could reshape the global map of innovation in ways that few people expect.

Dr. Robert Cialdini, author of Influence - 5 million copies sold, and one of the most important books Warren Buffett says he's ever read - has spent decades studying why people say yes.  He reveals the psychological forces shaping our decisions, why tiny changes can dramatically influence outcomes, and how the most effective communicators get people to yes without anyone feeling pushed.  Once you understand these principles and hidden triggers, you'll start seeing them everywhere.

Most people think healthcare is broken by accident. Mark Cuban says it isn't. In part two of our conversation, he explains the hidden companies who really control healthcare, where AI is headed, and the biggest opportunities most people are missing. He also shares the advice he gives young people, the three “superpowers” he believes matter more than talent, network, or money, and the one question he thinks everyone should ask themselves.

The NBA thought it was selling basketball. Mark Cuban thought it was selling something else. That insight shaped how he has built companies, evaluated opportunities, and challenged entire industries. The lesson starts with basketball. It ends somewhere much bigger.  He also shares the skill he values most in entrepreneurs, and how AI is changing the way ambitious people learn.

What if those brief conversations - with a barista, a neighbor, or someone sitting next to us - matter far more than we realize? Gillian Sandstrom, a University of Sussex psychologist and author of Once Upon a Stranger, explores why we're so reluctant to talk to people we don't know, what happens when we do, and how seemingly small interactions can add up to a richer, happier, and more connected life.

The wind stops blowing. The sun goes down. What happens next? Former U.S. Secretary of Energy Ernest Moniz explains why the transition to clean energy may be far more complicated than most people realize. In one of the most clear-eyed conversations about our energy future, Moniz pulls back the curtain on what it will actually take to build energy that is clean, reliable, and affordable - and why some of the hardest challenges have little to do with solar panels or wind turbines. He reveals which emerging technologies - from hydrogen to nuclear fusion - could reshape the future of energy, why s

We think of North Korea as a communist dictatorship. But Jonathan Cheng, the Wall Street Journal’s China Bureau Chief and former Korea Bureau Chief, says that misses the real story. He argues North Korea functions more like a religion -  complete with rituals, worship, and a ruling family treated like immortals. Once you hear it, you can’t unsee it. His new book is Korean Messiah.

When people think about war, they picture missiles and mushroom clouds. But what if the greatest threats today are the ones most people never see coming? Christine Wormuth, former U.S. Secretary of the Army and current leader of the Nuclear Threat Initiative, explains why some of today’s biggest dangers are quieter, harder to detect, and easier to unleash than most people realize.

Most people see the world as the U.S. vs. China.But the real power shift is happening elsewhere. Richard Fontaine, CEO of the Center for a New American Security and a former senior advisor at the National Security Council and the U.S. State Department, shows which countries are quietly shaping the next world order - and why the biggest power shifts are happening far from the spotlight.

Inflation, interest rates, AI, tariffs, the dollar… Most people treat them as separate stories but actually, they’re not. Former Council of Economics Chair Jason Furman explains how these forces are all connected - and why most people are missing the bigger picture. What’s really driving inflation, why the dollar’s power may be slipping, and why the biggest risk isn’t what most people are watching. A conversation about the hidden forces shaping the economy - and what comes next.

“We trained a whole country.” It sounds like an exaggeration. It’s not - according to Patrick McGee, author of Apple in China. So what actually happened in China?

Dr. Tom Mihaljevic, CEO of Cleveland Clinic and a leading heart surgeon, explains how medicine is already changing in ways most people don’t see. He has spent his career performing complex heart surgeries and now leads one of the world’s top hospitals. A conversation about what’s changing in care and what it means for patients right now.

Iran briefly showed it could choke off a waterway carrying nearly a fifth of the world’s oil. That’s the visible threat. The real risk may be something else entirely. Former Deputy National Security Advisor and U.S. Special Representative to Iran Elliott Abrams breaks down where Iran's strategy backfired, whether those in power in Tehran can hold on, and why the most dangerous consequence could outlast the war itself. -------------------------- Exciting news! We’ve been nominated for a Webby Award — one of the top honors for podcasts.   If you enjoy the show, you can vote for 3 Takeaways here:

We’re entering a world where life itself could become programmable. What if creating new forms of life becomes as simple as writing code?  Geneticist Adrian Woolfson explains how close we are — and why the consequences could be extraordinary.

Is the war with Iran actually a turning point for the Middle East? Dan Kurtzer - former U.S. Ambassador to Israel and Egypt, advisor to presidents, and peace negotiator - has seen these moments up close, when expectations surge - and the outcome looks nothing like the promise. His unfiltered take on Iran - and what actually changes after a war like this.

Love him or hate him, Elon Musk has upended entire industries - from cars to rockets - by doing things differently. Jon McNeill, former president of Tesla, reveals the thinking behind Tesla and SpaceX that drives radical innovation - and shows how anyone can apply it.

A few paragraphs from Washington once stopped oil tankers in their tracks halfway around the world - no navy, no missiles.  Eddie Fishman, who helped design and implement U.S. sanctions and economic warfare policies, explains how these quiet battles shape global power.  If countries can inflict real damage without firing a shot, what does power look like in this new kind of war - and how vulnerable are we?

Scientists are finding tiny fragments of plastic inside the human body - including the brain. Dr. Matthew Campen of the University of New Mexico explains how they get there - and why the biggest source may surprise you.

The government feels louder and faster than ever: executive actions, constant disruption, everything happening at once.  But Yuval Levin of the American Enterprise Institute argues that all this motion may be masking something deeper. He explains why durable change comes from laws passed by Congress - not one-off deals- and why the shift from rule-making to deal-making could shape the future in unexpected ways.

The rules of quantum physics aren’t just strange - they’re usable. Particles can exist in multiple states at once. Observation can reshape reality.  Now, scientists are turning those quirks into machines that could solve problems today’s computers simply can’t touch. Princeton Engineering Dean Andrew Houck breaks down what quantum computing really is, what it can (and can’t yet) do, and why it could transform fields from drug discovery to energy. A clear-eyed look at the weirdest laws of the universe and the revolutionary technology they may soon power.

The Constitution isn’t just a statement of ideals. It’s a framework for power - built to divide authority so that no single institution can fully control the law. But that design has a consequence: it slows decisions and complicates action. Is that inefficiency a weakness - or the very mechanism that protects liberty? Drawing on his experience at the center of federal rule-making, Harvard Law School’s Cass Sunstein explores how these constitutional guardrails actually work, why they were designed to restrain concentrated authority, and what we risk losing when they begin to erode. This isn’t a

We all love the thrill of winning - the house, the promotion, the deal. But as Nobel laureate Richard Thaler explains, some of our biggest “wins” are actually the moments we set ourselves up to lose. Thaler breaks down why we overbid, overpay, and talk ourselves into choices we regret. And he shares simple tricks to help you catch yourself before you make a mistake you can’t undo.

The American Dream promises that hard work leads to a better life. But for many children today, that promise depends less on effort and more on where they grow up. Raj Chetty, a Harvard professor and the founder of Opportunity Insights, has spent years following millions of lives to understand what truly drives economic mobility. His findings challenge long-held assumptions about opportunity in America. If the American Dream has started to feel like a coin flip, what’s quietly shaping the odds? And what would it take to give more children a real chance to get ahead? In this conversation, we ex

Federal Judge Jed Rakoff has spent decades inside the justice system - as a prosecutor, a defense attorney, and now a judge. In this conversation, he challenges how we think justice works and explains why outcomes often have little to do with guilt or innocence.

We tend to think of laughter as a reaction to something funny. A joke. A punchline. A moment of humor. But in real conversations, laughter shows up in ways that matter far more than we realize. Neuroscientist Sophie Scott CBE explores why we laugh, how laughter actually works, and the many roles it plays in our relationships - from bonding and relief to concealment and control.  Sophie Scott is a professor at University College London and a leading researcher on the science of laughter.

Elon Musk and Geoffrey Hinton warn of an AI-driven job apocalypse. MIT’s David Autor, one of the world’s leading thinkers on how technology reshapes work, says the real danger lies somewhere else. The biggest risk of AI isn’t mass unemployment - it’s whether human skills and expertise will still matter. David explains how AI could expand middle-class opportunity by lowering barriers to high-value work, why past technologies created more new jobs than they destroyed, and what we need to get right to make this moment a hopeful one.

Jack Goldsmith, who once ran the Justice Department office that advises presidents on what they can and can’t legally do, takes on some of the hardest questions about the limits of the president’s power — from changing the government to the use of military force abroad, including the invasion of Venezuela. Drawing on his experience inside the executive branch, he looks at why the limits on presidential power are more fragile than they appear, how precedent quietly expands executive authority, and what that means for the future of the presidency.

Most people quit their New Year's resolutions by March. The reason why might surprise you. University of Chicago professor Ayelet Fishbach has spent decades studying why we fail at goals. Her finding: willpower is overrated. What matters is something entirely different. In this episode, Fishbach reveals what actually separates those who succeed from those who quit and the strategies that make goals stick.

Some insights change how you see the world. From the White House to the frontiers of AI drug discovery, we’ve gathered the most powerful moments from a year of extraordinary conversations.  This 2025 highlights episode brings you the thinkers and leaders who challenged assumptions, revealed hidden patterns, and reframed the biggest questions of our time.  - Mark Buchanan (Physicist): The hidden patterns behind catastrophes from wildfires to stock market crashes - Cass Sunstein (Harvard Law Professor): What Facebook’s emotional manipulation experiment really revealed - Susan Magsamen (Johns Hop

Dr. David Agus, Professor of Medicine and Engineering at the University of Southern California and Founding CEO of the Ellison Medical Institute, treats presidents, CEOs and cultural icons and has spent decades studying one question: What determines how long and well we live? His answer is hopeful: Only 4% is genetic. The other 96% is under your control. In this episode, he reveals why elephants rarely get cancer, why giraffes never get heart disease, and what inflammation does to nearly every organ in your body. He also shares the simple, proven habits that matter more than DNA, and destroys

Nicholas Burns spent 2021 to 2025 in Beijing as US Ambassador to China, witnessing up close the forces shaping the world's most dangerous rivalry. Sitting across from Xi Jinping and living in China, he saw firsthand how dangerously close the world is to a crisis. Some of it genuinely terrified him. Our conventional wisdom about China? Outdated. And dangerously wrong. In this episode, he reveals the alarming "nightmare scenario" almost no one is talking about, why a single unanswered phone call could spark disaster, and what we're getting wrong about China and what China is getting wrong about

Sleep shapes your mood, memory, immune system, and long-term health, yet most of us aren’t getting enough.  Harvard Medical School and Mass General Brigham sleep scientist Dr. Elizabeth Klerman shares the three easiest science-backed changes proven to improve your sleep tonight, plus the myths that make things worse.   If you’re struggling to fall asleep, waking at 3 a.m., or dragging through the day, this episode is for you.

In a Paris hospital delivery room, Thomas Chatterton Williams, writer for The Atlantic and author of Self-Portrait in Black and White, held his newborn daughter for the first time. Blonde hair. Blue eyes. And in that instant, everything he thought he knew about race shattered. Thomas lives the questions about race and identity that most of us only debate. The son of a Black father who grew up under Jim Crow and a white mother, he had accepted America's racial categories without question. Until he couldn't. What he decided is radical. Controversial. And will challenge how you think about identi

What if fatigue, fear, and even failure aren’t real limits, but signals from the brain trying to protect us? Nick Thompson, CEO of The Atlantic and former Editor-in-Chief of Wired reveals the surprising psychology behind fatigue, focus, and fear and how our biggest limits often come from within. Nick isn’t just one of the most thoughtful leaders in media, he’s also a record-breaking ultramarathoner who’s learned that endurance begins in the mind. This conversation will change how you think about performance, aging, and the power of effort itself. Nick's wonderful new book is The Running Ground

We’re told youth is life’s peak — but what if that story is wrong? Stanford psychologist Laura Carstensen reveals how time itself reshapes what we value and how we find meaning. Her research offers profound lessons for living well at every age — and for finding more meaning in the moments we have.  It’s a conversation that will change how you think about time, happiness, and life itself.

We’ve entered a new age. Where nature once took a million years to make a few genetic changes, scientists can now make billions in an afternoon — and even imagine adapting humans for life beyond Earth. George Church, a Harvard geneticist, pioneer of the Human Genome Project, and founder of more than 50 biotech companies, helped lay the foundation for CRISPR, personal genomics, and even de-extinction. In this episode, he explains how biotechnology, AI, and materials science are converging to transform life itself -  from reversing aging and curing disease to resurrecting lost species like the w

AI doesn’t just predict our behavior — it can shape it. Cass Sunstein, Harvard professor and co-author of Nudge, reveals how artificial intelligence uses classic tools of manipulation — from scarcity and social proof to fear and pleasure — to steer what we buy, believe, and even feel. Its influence is so seamless, we may not even notice it. The battle for the future isn’t for our data — it’s for our minds. In a world this personalized, how do we keep control of our own minds?

When Vladimir Putin first rose to power, few expected him to become the world’s most confrontational autocrat. Former U.S. Ambassador to Russia Michael McFaul, who has studied and worked with Putin for decades, explains what changed — and why.  From paranoia about democracy to the drive to rebuild Russia’s sphere of influence, McFaul shows how personal power and national destiny became one and the same. His insights reveal not just who Putin is, but what he wants next.

The dollar has been one of America’s most powerful weapons and a major source of global influence, in ways few fully realize. It doesn’t just shape trade and finance; it also gives the U.S. a unique window into the world’s financial flows.  But what if that power is beginning to slip? Harvard’s Ken Rogoff examines the mounting pressures that could threaten the dollar’s supremacy — and reveals how a cornerstone of U.S. power could also become its Achilles’ heel.

Grief and trauma are part of being human, yet most of us have little idea what to expect. We picture them as overwhelming, endless, and all-consuming. But what if that story is wrong? Columbia professor George Bonanno reveals a surprising truth about how people actually cope — and it may change the way you think about loss.